The Fresh Start to resolving your joint Pain- All you need to know about Stem cells


Prajakta Shendge

September 9, 2021

Stem Cell Therapy for Joint Pain

Despite advances in science, many conditions still have limited treatment options. Joint pain and inflammation, due to knee osteoarthritis conditions, for example, have been difficult to treat and manage

This leaves many people suffering day to day from knee pain due to arthritis, tendonitis, and related conditions. An estimated 350 million people worldwide have arthritis. Luckily, with regenerative medicine therapy on the rise, there are growing opportunities to treat patients with chronic pain and immobility.

Where Do We Get Stem Cells from?

To better understand the process of stem cell injection, it is essential we discuss the source of these cells. There are several areas in the human body which are used by our experts to harvest potent cells for treatments.

Bone marrow is one common site for harvesting adult stem cells. These cells are beneficial in their ability to “vascularize” an area. That means they can bring in new blood channels. These new vessels, in turn, carry nutrients and healing factors to the area.

These cells can support other stem cells to build new tissue do so through a phenomenon called the paracrine signalling. Paracrine signalling is a type of cell-to-cell communication wherein one cell releases factors that impact the function of other cells. It is how cells “talk” within the human body.

Adipose-derived stem cells (ADSCs) are another source that comes from fat. They consist mostly of mesenchymal stem cells (MSCs), which contain high levels of restorative properties.

Amniotic fluid and placental blood and tissue are other rich source of stem cells. These stem cells are not sourced from the womb while the baby is gestating. Rather, medical professionals gather it after a baby is born.

They can either collect the fluid during caesarean sections or harvest it from donated placentas. These collection techniques do not raise the same ethical and moral concerns as other approaches, such as embryonic stem cells (ESCs). Currently, these are not commonly used in the UK.

Human umbilical cord tissue is another excellent source for stem cell therapy. It is rich in mesenchymal stem cells (MSCs). These cells work particularly well to reduce inflammation. They also help to modify the immune system. This is especially important for people with rheumatoid arthritis (RA), which is an autoimmune condition. The body attacks itself, damaging the organs. Preventing this occurrence in the first place is one of the best treatments. The same goes for other autoimmune conditions and is not currently commonly used in the UK.

Our team at Regenesiss Orthobiologics, recently helped a 93 year old gentleman to treat and successfully manage his hip pain due to Hip Arthritis. Watch his testimonial.

What are the current benefits of stem cell therapy?

Previously, people with joint pain and inflammation did not have many choices. Doctors might prescribe them anti-inflammatory medications or periodic steroid injections to reduce pain. They might also administer hyaluronic acid injections (viscosupplementation) for early osteoarthritis pain or recommend physical therapy or joint replacement surgery.

These conservative treatments, unfortunately, are not that effective and only short-acting. The joint replacement surgery option is invasive and suitable for only end-stage osteoarthritis.

The same is not true of regenerative therapy procedures such as stem cell procedures. Stem cell therapy can help pain, inflammation and function resulting from many musculoskeletal conditions including:

Knee osteoarthritis
Patella tendinitis
Rotator cuff tendonitis in the shoulder
Achilles tendinitis
Tennis elbow
Hip osteoarthritis
Shoulder osteoarthritis
Ankle osteoarthritis
Cartilage defects in any joint

The stem cells encourage the body’s own healing process, as well as provide the building blocks for new tissue.

However, a stem cell injection may not work immediately, because it can take time for cells to exert their effects. In some cases, more than one injection may be necessary. Our experts may put you on a personalised tailor-made treatment plan that is suitable for you.

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